Characterisation of Chitosan Coated Liposomes as Putative Delivery Systems

Recent Advances in Structural Biology and Drug Discovery (BIODRUG 2023): Abstract Book 2023
Kārlis Pajuste, Ruslan Muhamedejev, Davis Lacis, Nadiia Pikun, Martins Rucins, Māra Plotniece, Aiva Plotniece, Arkadij Sobolev

Various drawback of drugs, such as rapid clearance, suboptimal biodistribution, low intracellular absorbtion and toxicity which may limit their therapeutic efficacy, can be diminished by loading the drug into delivery systems. Decoration of liposomes with chitosan is one of the approaches to enhance of their physico-chemical and biochemical properties. The coating mechanism of liposomes with chitosan is mainly based on electrostatic forces.

Keywords
chitosan, liposomes, 1,4-DHP

Pajuste, K., Muhamedejev, R., Lacis, D., Pikun, N., Rucins, M., Plotniece, M., Plotniece, A., Sobolev, A. Characterisation of Chitosan Coated Liposomes as Putative Delivery Systems. In: Recent Advances in Structural Biology and Drug Discovery (BIODRUG 2023): Abstract Book, Latvia, Riga, 18-19 September, 2023. Riga: 2023, pp.P20-P20.

Publication language
English (en)