Antiradical Activity of Arylmethyl Meldrum’s Acid Salts
Balticum Organicum Syntheticum 2024: Abstract Book
2024
Aleksandra Ofrosimova,
Laima Bērziņa,
Kārlis Cepurnieks-Cepurītis,
Inna Juhņeviča,
Inese Mieriņa
Arylmethyl Meldrum’s acids mainly quench radicals through a sequential proton loss - electron transfer (SPLET) mechanism. In this mechanism deprotonation of the antioxidant is typically the rate-determining step, therefore pre-deprotonation (or salt formation) is expected to increase the activity of the compound. Here we have used various amines to deprotonate arylmethyl Meldrum’s acid 1 and tracked the changes in radical scavenging ability.
Keywords
antioksidanti, arilmetilmeldrumskābes, sāļi
Hyperlink
https://boschem.eu/bos2024/abstract-book/
Ofrosimova, A., Bērziņa, L., Cepurnieks-Cepurītis, K., Juhņeviča, I., Mieriņa, I. Antiradical Activity of Arylmethyl Meldrum’s Acid Salts. In: Balticum Organicum Syntheticum 2024: Abstract Book, Latvia, Riga, 7-10 July, 2024. Riga: 2024, pp.34-34.
Publication language
English (en)