The first experimental results on the functioning of liquid crystal cells doped with CoFe2O4 nanoparticles are presented. Transmission spectra in the visible and near-infrared range, dynamic parameters of the Fredericks effect, refractive characteristics, as well as wetting angles of the mesophase sensitized surfaces have been obtained. The measured surfaces were the K8 Crown glass, the conductive ITO and the ITO treated with a surface electromagnetic wave. The experiment was performed in order to establish the prospect of using such reliefs as a novel liquid crystal composite orientator sensitized with CoFe2O4 nanoparticles. A color change of the liquid crystal matrix, its refractive coefficients alterations, and the variation of inclination angle of the sensitized liquid crystal droplets on the considered reliefs were established. The time reaction parameters and the medium relaxation parameters were measured. It was proposed that the liquid crystal composition is a kind of an immersion medium that preserves properties of the introduced nanoparticles, which expands their application scope in optoelectronics and biomedicine