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Publikācija: Biomechanical Properties and Resistens to Proteolytic Degradation of Glutaraldehyde Treated Human Pericardium

Publication Type Conference paper
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Biomechanical Properties and Resistens to Proteolytic Degradation of Glutaraldehyde Treated Human Pericardium
Field of research 2. Engineering and technology
Sub-field of research 2.6 Medical engineering
Authors Vladimirs Kasjanovs
Aris Lacis
Iveta Ozolanta
Valts Ozolins
Lauris Smits
Keywords pericardium, glutaraldehyde, properties
Abstract Pericardium is commonly used for repair of congenital heart defects [Paez, 1999]. Autologous pericardium can be used in its fresh non-treated state, or after chemical fixation with glutaraldehyde solution as a biomaterial for surgical repair of congenital heart anomalies. However, there are not many studies about changes of biomechanical properties of human pericardium after treating with glutaraldehyde. Influence of different concentration and exposition time of glutaraldehyde on resistance of human pericardium to proteolytic degradation needs further investigations. [Vincentelli, 1998, Stacchino, 1998] The aim of this experimental study is to investigate changes of biomechanical properties and resistance to proteolytic degradation of human pericardium, which was used as patch material for congenital heart surgery, after harvesting and treatment with glutaraldehyde solution.
Reference Kasjanovs, V., Lacis, A., Ozolanta, I., Ozolins, V., Smits, L. Biomechanical Properties and Resistens to Proteolytic Degradation of Glutaraldehyde Treated Human Pericardium. In: 16th Congress of the European Society of Biomechanics: Abstracts of ESB Congress, Switzerland, Lucerna, 6-9 July, 2008. Lucerna: Elsvier, 2008, pp.62-62.
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