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Publikācija: Calcium Phosphates for Clinical Application with Variable Phase Composition: Synthesis and Characterization

Publication Type Scientific article indexed in ERIH database, in INT1 or INT2 category journals
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Calcium Phosphates for Clinical Application with Variable Phase Composition: Synthesis and Characterization
Field of research 2. Engineering and technology
Sub-field of research 2.4 Chemical engineering
Authors Kristīne Šalma-Ancāne
Līga Bērziņa-Cimdiņa
Natālija Borodajenko
Zilgma Irbe
Liene Plūduma
Keywords calcium phosphates, synthesis, phase composition
Abstract Hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) represent the main types of calcium phosphates use for bone and dental surgery. HAp is thermodynamically the most stable phase in physiological conditions and has the ability to form direct chemical bonding with living tissues while β-TCP is a resorbable material and stimulates new bone formation. Biphasic calcium phosphates (BCP) were developed to combine the high bioactivity of HAp and bioresorbability of β-TCP. These properties can be controlled by varying HAp/β-TCP ratio. Hydroxyapatite (HAp), β-tricalcium phosphate (β-TCP) and mixtures of HAp/β-TCP in different proportions were synthesized by wet chemical precipitation method in aqueous medium using calcium hydroxide suspension and orthophosphoric acid solution as starting materials. This method is characterized by simple process, low cost and easy application in industrial production. The aim of this study was to investigate the influence of wet chemical precipitation conditions on calcium phosphates to control not only the phase composition, but also chemical composition, particle morphology and sinterability. The phase identification, chemical composition, morphological characteristics and sintering behaviour were investigated by X-ray powder diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy and scanning electron microscopy (SEM). The phase composition of calcium phosphates is found to be highly dependent on the changes in technological parameters such as temperature, pH of synthesis and thermal processing.
Reference Šalma-Ancāne, K., Bērziņa-Cimdiņa, L., Borodajenko, N., Irbe, Z., Plūduma, L. Calcium Phosphates for Clinical Application with Variable Phase Composition: Synthesis and Characterization. Stomatologija : Baltic Dental and Maxillofacial Journal, 2009, Supplement 6, pp.41-42. ISSN 1392-8589. e-ISSN 1822-301X.
ID 5478