Separation of Selected Heptacoordinated Derivatives of Goshchava-Silanates for HPLC

Journal of Liquid Chromatography & Related Technologies 2009
M. Kluska, K. Pupowski, I. Chrzascik, R. Gadzala-Kopciuch, M. Michael, Edvards Liepiņš, N. Erchak

Optimum conditions of separation and determination was studied of two newly synthesized heptacoordinated benzyl derivatives from the group of Goshchava-silanates: Homo{O,O′,O″,O‴-oxalic acid's Si-[N-benzylaminiomethyl]-Si,Si-dihydroxysilanate} and Homo{O,O′,O″,O‴-oxalic acid's Si-[N-benzylaminiomethyl]-Si,Si-diethoxysilanate}. In the carried out investigation, we considered three stationary phases (octadecyl, octyl, phenylbutyl) and two mobile phases (acetonitrile and dichloromethane) in various intensities of flow. The best selectivity and the highest separation factor (α = 9.08) was obtained using the mobile phase acetonitrile (100%) and the phenylbutyl column. To reliably optimize the process of separation and determination of the compounds on the phenylbutyl column, the validation of prepared methodology was done.

Keywords
Determination, Heptacoordinated organosilicon derivatives, HPLC, Separation
DOI
10.1080/10826070902901549
Hyperlink
http://www.tandfonline.com/doi/full/10.1080/10826070902901549#.VE9Y-sscQ5s

Kluska, M., Pupowski, K., Chrzascik, I., Gadzala-Kopciuch, R., Michael, M., Liepiņš, E., Erchak, N. Separation of Selected Heptacoordinated Derivatives of Goshchava-Silanates for HPLC. Journal of Liquid Chromatography & Related Technologies, 2009, Vol.32, Iss.10, pp.1505-1515. ISSN 1082-6076. e-ISSN 1520-572X. Available from: doi:10.1080/10826070902901549

Publication language
English (en)