The main components of human factor are examined and analyzed in this article, including physiological and psychological components. These mentioned components are divided in nine groups, and analyzed interaction between these groups. The list of groups of properties which form the human factor is based mainly on the development of a professional training system and identification and singling out of its tasks and goals. The research and improvement of the professionally most essential professional qualities of the crew materialises in the context of identifying the said qualities in a common integral structure covering the human factor. Therefore, the research of the most significant components of the human factor should materialise as a body within a united system, based on internationally accepted and recognised standards, as well as in consideration of individual psycho-physiological properties. The most significant property components of the human factor which may have a major influence on flight safety are named and described in this paper.