It is possible to integrate in the clothes different cooling systems operating at different cooling principles - thermodynamic methods. In the world is already discovered and patented smart clothes and other articles, with integrated thermoelectric converters. Such a garment manufacturing process have to provide a small garment weight, durability and safety, operational efficiency, minimal current flow, clothing comfort, air and vapor permeability and low production costs. Manufacturing of smart clothes with integrated microclimate control system request for the research process to optimize the cooling function. Experiments with a thermoelectric module - Peltier element - and materials of copper, bronze and steel in different thread thickness and density, as well as copper foil, it is observed, that the copper foil provides the necessary heat removal, while the copper gauze, which by its structure and properties would be more suitable for the integration in clothing, produce insufficient results.