Today, mankind's sustainable existence is threatened by rapid economic, technological and demographic developments. The growing pace and inertia increasingly threatens the possibility of timely countermeasures. Possible backlash time ever decreasing and sustainable human existence is threatened. In case if the system is approaching the pace of change in the time required to stabilization of the system again, threats require urgent action. At the moment when the system exceeds the rate of change of response time, the system will become unsustainable and doomed to extinction. Despite the specific differences in quality and a huge diversity of complex structures, systems have some basic elements that allow them to analyze with similar basic tools. The paper deals with sustainable development indicators optional prerequisites, identified in the public system of major subsystems and under the six fundamental environmental characteristics that are six environment-set basic orientor’s (existence, effectiveness, flexibility, security, adaptability and co-existence), which applies to all the autonomous self-organizing systems, plus a three system- set basic orientor’s (reproduction, psychological needs and responsibility) that are peculiar for self-reproductive, sensitive and conscientious beings. Each orientor represents a unique need (requirement). This means that each of them paid minimal attention, and that one orientor deficit compensation over the other main orientor dominance is not possible. Livability requires each main orienteer adequate satisfaction. Self-organization process inside the system makes constantly changes, which changes the overall system development process, but they sometimes tend to be cyclical in nature. Taking into account this aspect it is possible to select appropriate indicators, which already take into account the cyclical nature of the system changes. Most importantly retain flexibility and the ability to change the indicator groups fast enough to keep up with changing conditions and ensure the overall viability of the system.