Design, Synthesis, and Bioactivity Evaluations of 3- Methylenechroman-2-one Derivatives as Thioredoxin Reductase (TrxR) Inhibitors

Anna Ņikitjuka, Melita Ozola, Kristaps Krims-Davis, Raivis Žalubovskis

1 Table of Contents TrxR1 absorbance plot in the presence of 2 mM of the tested compounds 5 and coumarin (representative example)........................................................................................................................................................ 3 Dose- response curve for compound 5e, TrxR1 IC50 .................................................................................... 3 Dose- response curve for compound 5e on different cell lines (representative examples) ........................... 4 Stability studies of compound 5a by 1H-NMR ...........

Date
11.01.2023.
Keywords
3- Methylenechroman-2-one Derivatives
Hyperlink
https://chemistry-europe.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Fcmdc.202300504&file=cmdc202300504-sup-0001-misc_information.pdf