RTU Research Outputs and Resources: Reasearch Staff

Information about Author

Name, Surname:

Kristaps Jaudzems

Department:

(14821) Ķīmijas katedra

Scientific Degree:

Doktors

E-mail:

Kristaps.Jaudzems(at)edu.rtu.lv

Publications

55 items found, displaying 1 to 10.

Biomimetic Spider Silk by Crosslinking and Functionalization with Multiarm Polyethylene Glycol
(2024)

Viktors Romaņuks, Jēkabs Fridmanis, Benjamin Schmuck, Anna Līna Bula, Alons Lends, Kristine Senkane, Gundars Leitis, Sergejs Gaidukovs, Krišjānis Šmits, Gints Smits, Anna Rising, Kristaps Jaudzems
Scientific article indexed in SCOPUS or WOS database

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
(2023)

Vadims Kovada, Chrislaine Withers-Martinez, Raitis Bobrovs, Helēna Cīrule, Edgars Liepiņš, Solveiga Grinberga, Fiona Hackett, Christine R. Collins, Agrita Kreicberga, Maria Belen Jimez-Diaz, Inigo Angulo-Barturen, Dace Rasiņa, Edgars Sūna, Kristaps Jaudzems, Michael J. Blackman, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
(2023)

Olga Bobileva, Raitis Bobrovs, Evelīna Elva Sirma, Iveta Kaņepe, Anna L. Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
Scientific article indexed in SCOPUS or WOS database

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials
(2022)

Raitis Bobrovs, Emīls Edgars Basens, Laura Drunka, Iveta Kanepe, Sofija matisone, Karlis Kristofers Velins, Victor Andrianov, Gundars Leitis, Diāna Zeļencova-Gopejenko, Dace Rasiņa, Aigars Jirgensons, Kristaps Jaudzems
Scientific article indexed in SCOPUS or WOS database

Total Synthesis of the Proposed Structure of Uncarialin A
(2021)

N.V Ūdris, Kristaps Jaudzems, Gints Šmits
Scientific article indexed in SCOPUS or WOS database

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency
(2020)

Dace Rasiņa, Georgijs Stakanovs, Iveta Kaņepe-Lapsa, Raitis Bobrovs, Kristaps Jaudzems, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D
(2019)

R. Zogota, L. Kinena, C. Withers-Martinez, M.J. Blackman, R. Bobrovs, T. Pantelejevs, I. Kanepe-Lapsa, V. Ozola, Kristaps Jaudzems, Edgars Sūna, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Azole-Based Non-Peptidomimetic Plasmepsin Inhibitors
(2018)

L. Kinena, G. Leitis, I. Kanepe-Lapsa, R. Bobrovs, Kristaps Jaudzems, V. Ozola, Edgars Sūna, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

2-Aminoquinazolin-4(3H)-One Based Plasmepsin Inhibitors with Improved Hydrophilicity and Selectivity
(2018)

D. Rasiņa, G. Stakanovs, O.V. Borysov, T. Pantelejevs, R. Bobrovs, I. Kanepe-Lapsa, K. Tars, Kristaps Jaudzems, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors
(2018)

M.H. Charlton, R. Aleksis, A. Saint-Leger, A. Gupta, E. Loza, L. Ribas De Pouplana, I. Kaula, D. Gustina, M. Madre, D. Lola, Kristaps Jaudzems, G. Edmund, C.P. Randall, L. Kime, A.J. O`Neill, W. Goessens, Aigars Jirgensons, P.W. Finn
Scientific article indexed in SCOPUS or WOS database

Information about Author

Publications

Biomimetic Spider Silk by Crosslinking and Functionalization with Multiarm Polyethylene Glycol
(2024)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
(2023)

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
(2023)

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials
(2022)

Total Synthesis of the Proposed Structure of Uncarialin A
(2021)

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency
(2020)

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D
(2019)

Azole-Based Non-Peptidomimetic Plasmepsin Inhibitors
(2018)

2-Aminoquinazolin-4(3H)-One Based Plasmepsin Inhibitors with Improved Hydrophilicity and Selectivity
(2018)

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors
(2018)

Supervised Dissertations

Structural and Functional Studies of Proteins Involved in the Regulation of Fatty Acid Metabolism
(2023)

Information about Author

Publications

Biomimetic Spider Silk by Crosslinking and Functionalization with Multiarm Polyethylene Glycol (2024)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity (2023)

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors (2023)

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials (2022)

Total Synthesis of the Proposed Structure of Uncarialin A (2021)

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency (2020)

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D (2019)

Azole-Based Non-Peptidomimetic Plasmepsin Inhibitors (2018)

2-Aminoquinazolin-4(3H)-One Based Plasmepsin Inhibitors with Improved Hydrophilicity and Selectivity (2018)

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors (2018)

Supervised Dissertations

Structural and Functional Studies of Proteins Involved in the Regulation of Fatty Acid Metabolism (2023)

Biomimetic Spider Silk by Crosslinking and Functionalization with Multiarm Polyethylene Glycol
(2024)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
(2023)

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
(2023)

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials
(2022)

Total Synthesis of the Proposed Structure of Uncarialin A
(2021)

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency
(2020)

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D
(2019)

Azole-Based Non-Peptidomimetic Plasmepsin Inhibitors
(2018)

2-Aminoquinazolin-4(3H)-One Based Plasmepsin Inhibitors with Improved Hydrophilicity and Selectivity
(2018)

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors
(2018)

Structural and Functional Studies of Proteins Involved in the Regulation of Fatty Acid Metabolism
(2023)