Copper-Catalyzed Intramolecular N-Arylation of Hydroxamic Acids

International Conference on Organic Synthesis: Program & Abstracts 2010
Tatjana Kukoša, Nadežda Trjufilkina, Mārtiņš Katkevičs

A variety of N-alkyloxy-2-oxyindole derivatives bearing substituents at the phenyl ring, 3-position and N-O group were prepared with good to excellent yields according to the elaborated procedure. The method is applicable for synthesis of 2-quinolinone 3 as well, although longer reaction time is necessary. Initial results for intermolecular arylation of hydroxamic acids will be also presented.

Keywords
transition-metal-catalysis, copper, hydroxamic acids

Kukoša, T., Trjufilkina, N., Katkevičs, M. Copper-Catalyzed Intramolecular N-Arylation of Hydroxamic Acids. In: International Conference on Organic Synthesis: Program & Abstracts, Latvia, Rīga, 27-30 June, 2010. Riga: RTU, 2010, pp.122-122.

Publication language
English (en)