Titanium dioxide ceramic powder with the average particle size of 200 nm was used for the preparation of ceramic rods. Industrial scale equipment was used to perform the preparation of extrusion mass and extrusion. Microstructure of samples before sintering and after sintering in different temperatures was investigated. In current research sintering temperatures from 1100 °C up to 1450 °C was used. Results obtained showed that the microstructure of the samples after sintering depends on the mass preparation and extrusion parameters. At low temperatures sintered samples exhibit different microstructure and porosity in the inner and outer part of the samples. Scanning electron microscopy, high temperature microscope and X-ray diffraction was used for the characterisation of the samples obtained. The changes in density and microstructure after sintering was investigated and related to the extrusion process parameters.