Reactivity Studies of 2,6‐Ditriazolylpurine Nucleosides with Nucleophiles
XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids: Poster Abstracts 2012
Armands Kovaļovs, Irina Novosjolova, Ērika Bizdēna, Māris Turks

Reaction of 2,6-ditriazolylpurine nucleosides with nucleophiles is mild and efficient route to C6 derivatization of purine base. To explore scope and limitations of the method, we studied reactivity of various N- and S-nucleophiles as well as kinetics for selected reactions.


Keywords
ditriazolylpurine nucleosides, 1,3-dipolar cycloaddition reaction, fluorescence, nucleophilic substitution
Hyperlink
http://www.is3na.org/assets/events/Category%203-Nucleos%28t%29ide%20Probes%20%28109-153%29.pdf#page=4

Kovaļovs, A., Novosjolova, I., Bizdēna, Ē., Turks, M. Reactivity Studies of 2,6‐Ditriazolylpurine Nucleosides with Nucleophiles. In: XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids: Poster Abstracts, Canada, Montreal, 5-9 August, 2012. [S.l.]: IS3NA, 2012, pp.112-112.

Publication language
English (en)
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