2,6-Bis-(1,2,3-Triazolyl)Purines in Reactions with S-Nucleophiles

XVth International Conference "Heterocycles in Bio-organic Chemistry" : Program and Abstract Book 2013
Ērika Bizdēna, Irina Novosjolova, Māris Turks

The 1,2,3-triazolyl ring at C(6) position of purine has been shown as good leaving group in nucleophilic aromatic substitution reactions. In this study, we extended the range of nucleophiles with thioles. Triphenylmethyl mercaptan, thiophenol, dodecanthiol, benzylthiol, propane-1,3-dithiol, decane-1,10-dithiol were used for the substitution.

Keywords
Purine nucleosides
Hyperlink
http://www.bioheterocycles.eu/pictures/zinas/46.pdf

Bizdēna, Ē., Novosjolova, I., Turks, M. 2,6-Bis-(1,2,3-Triazolyl)Purines in Reactions with S-Nucleophiles. In: XVth International Conference "Heterocycles in Bio-organic Chemistry" : Program and Abstract Book, Latvia, Riga, 27-30 May, 2013. Riga: 2013, pp.59-59.

Publication language
English (en)