New Achievements in the Chemistry of Triazolyl Purine Nucleosides

Proceedings of the International Conference in the Chemistry and Chemical Technology 2014
Irina Novosjolova, Ērika Bizdēna, Māris Turks

Synthesis of novel 2- and 6-alkyl/arylthiopurine derivatives was developed. Reactions were carried out between 2,6-diazidopurine, 2,6-dichloropurine and 2,6-bis-triazolylpurine derivatives and different S-nucleophiles. In the case of 2-alkyl/arylthio-azidopurines the 1,3-dipolar cycloaddition reactions with alkynes have been made and novel purine-triazole conjugates were obtained.

Keywords
purine nucleosides, bis-triazolyl derivatives, 2,6-diazidopurine

Novosjolova, I., Bizdēna, Ē., Turks, M. New Achievements in the Chemistry of Triazolyl Purine Nucleosides. In: Proceedings of the International Conference in the Chemistry and Chemical Technology, Lithuania, Kaunas, 25-25 April, 2014. Kaunas: 2014, pp.178-181. ISSN 2351-5643.

Publication language
English (en)