Synthesis of New Fluorescent 9-Alkyl-6-amino-2-triazolyl Purines

16th Symposium on Chemistry of Nucleic Acid Components: Collection Symposium Series (M.Hocek, Ed.) 2014
Andrejs Šišuļins, Irina Novosjolova, Māris Turks, Ērika Bizdēna

The synthesis of new push-pull purines bearing an amino substituent at C(6) has been developed. additionally, a long chain alkyl or tetraethylene glycol (TEG) linker bearing active functional group for futher derivatisation was introduced at N(9). These purine derivatives showed strong fluorescence with emission around 430 nm when exited at 270-275 nm.

Keywords
fluorescent purines, bistriazolyl purines

Šišuļins, A., Novosjolova, I., Turks, M., Bizdēna, Ē. Synthesis of New Fluorescent 9-Alkyl-6-amino-2-triazolyl Purines. In: Collection Symposium Series. Vol.14. M.Hocek ed. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2014. pp.231-232. ISBN 978-80-86241-50-0.

Publication language
English (en)