Synthesis of Novel 2- and 6-Alkyl/Arylthiopurine Derivatives
Proceedings of 26th International Symposium on Organic Chemistry of Sulfur
2014
Irina Novosjolova,
Ērika Bizdēna,
Māris Turks
We have compared the reactivity of 2,6-bis-triazolylpurine, 2,6-dichloropurine and 2,6-diazidopurine nucleosides in the nucleophilic aromatic substitution reactions with thiols. In this way various 2- and 6-alkyl/arylthiopurine derivatives are available for further applications in medicinal chemistry which will be discussed in details.
Keywords
bis-triazolyl derivatives, purine nucleosides
Novosjolova, I., Bizdēna, Ē., Turks, M. Synthesis of Novel 2- and 6-Alkyl/Arylthiopurine Derivatives. In: Proceedings of 26th International Symposium on Organic Chemistry of Sulfur, Turkey, Istanbul, 24-29 August, 2014. Istanbul: 2014, pp.19-19.
Publication language
English (en)