Bovine Serum Albumin Adsorption onto Hydroxyapatite and Biphasic Calcium Phosphate Ceramic Granules

Key Engineering Materials 2017
Inga Jurgelāne, Armands Bušs, Dagnija Loča

Hydroxyapatite (HAp), beta tricalcium phosphate (β-TCP) and biphasic calcium phosphate (BCP) are calcium phosphate based ceramics and the most studied biomaterials for bone defect repair. One of the main requirements for these biomaterials is to be bioactive. The bioactivity of calcium phosphate based biomaterials can be evaluated by adsorption of proteins. The most abundant protein in the circulatory system is bovine serum albumin (BSA) therefore this protein is mostly used in vitro studies for bioactivity. BSA sorption results onto HAp and BCP ceramic granules are presented.

Keywords
Hydroxyapatite, biphasic calcium phosphate, bovine serum albumin, adsorption, simulated body fluid, phosphate buffer solution
DOI
10.4028/www.scientific.net/KEM.721.197
Hyperlink
https://www.scientific.net/KEM.721.197

Jurgelāne, I., Bušs, A., Loča, D. Bovine Serum Albumin Adsorption onto Hydroxyapatite and Biphasic Calcium Phosphate Ceramic Granules. In: Key Engineering Materials, Latvia, Riga, 3-4 November, 2016. Rīga: Trans Tech Publications, 2017, pp.197-201. ISSN 1662-9795. e-ISSN 1662-9795. Available from: doi:10.4028/www.scientific.net/KEM.721.197

Publication language
English (en)