Synthesis of Purine Based Organoselenium Compounds

12th Paul Walden Symposium on Organic Chemistry: Program and Abstract Book 2021
Agnija Ritere, Andris Jeminejs, Irina Novosjolova, Ērika Bizdēna

The importance of modified purine bases and purine nucleosides in medicine, biochemistry and biology is well recognized. Additionally, the interest in the organoselenium compounds has increased in the last two decades due to their various biological activities. The combination of purine scaffold with selenium moieties can lead to the compounds with interesting properties. Here we report the synthesis of 2-chloro-6-selanylpurine (2-4) and 2-triazolyl-6-selanylpurine (6) derivatives.

Keywords
2,6-bis(triazolyl)purines, selanylpurines, 2-triazolylpurines, nucleophilic aromatic substitution
Hyperlink
https://walden.osi.lv/wp-content/uploads/2021/10/12th_P.Walden_Symposium_Program.Abstract_BOOK.pdf

Ritere, A., Jeminejs, A., Novosjolova, I., Bizdēna, Ē. Synthesis of Purine Based Organoselenium Compounds. In: 12th Paul Walden Symposium on Organic Chemistry: Program and Abstract Book, Latvia, Riga, 28-29 October, 2021. Riga: RTU Press, 2021, pp.55-55.

Publication language
English (en)