The Selenylation of Purine Derivatives

Balticum Organicum Syntheticum 2022: Program and Abstract Book 2022
Agnija Ritere, Andris Jeminejs, Ērika Bizdēna, Irina Novosjolova, Māris Turks

Earlier we demonstrated that 1,2,3-triazole moiety at C(6) position of purine is a good leaving group in SNAr reactions with N, S, O, C and P-nucleophiles [1,2]. In this study we extended the range of nucleophiles with selenols. The synthetic routes to 6-selanyl-2- triazolylpurine nucleosides (4) and 2-chloro-6-selanylpurines (2) were developed and will be discussed.

Keywords
purine, SNAr, selanol, selanylpurine

Ritere, A., Jeminejs, A., Bizdēna, Ē., Novosjolova, I., Turks, M. The Selenylation of Purine Derivatives. In: Balticum Organicum Syntheticum 2022: Program and Abstract Book, Lithuania, Vilnius, 3-6 July, 2022. Vilnius: 2022, pp.136-136.

Publication language
English (en)