Highly Porous Ag- and/or Ti-Doped Calcium Phosphate Bioceramic Scaffolds: From Physicochemical to Biological Properties

XVIII ECerS Conference & Exhibition of European Ceramic Society Full Conference Book (electronic) 2023
Līga Stīpniece, Ingus Skadiņš, Dagnija Loča

Calcium phosphates (CaP) (i.e. hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP)) are widely used due to their excellent biocompatibility (Kalita et al., 2007). Porous bioceramic is the material of choice for non-load bearing bone implants. Besides filling bone defects, porous bioceramic can be used as bone tissue engineering scaffolds and as drug delivery devices. Ideally, porous bioceramic has interconnected macroporous network with pore size ≥100 µm to allow the bone tissue ingrowth. The aim was to develop Ag- and/or Ti-doped CaP (Ag- and/or Ti-CaP) bioceramic scaffolds. Due of their promising antibacterial properties, Ag(I) with Ti(IV) doping was used to reduce risk of bacterial infection.

Keywords
calcium phosphates, porous bioceramic, antibacterial ions, ion delivery

Stīpniece, L., Skadiņš, I., Loča, D. Highly Porous Ag- and/or Ti-Doped Calcium Phosphate Bioceramic Scaffolds: From Physicochemical to Biological Properties. In: XVIII ECerS Conference & Exhibition of European Ceramic Society Full Conference Book (electronic), France, Lyon, 2-6 July, 2023. Lyon: 2023, pp.1-1.

Publication language
English (en)