Today thermoregulation by clothing is developed by using in the high-tech way made heat regulating technologies or by integrating in the garment thermostatic electrical/electronic systems, such as systems with Peltier elements. The vest is developed as an experimental prototype of wearable electronic system for garment that can be used for needs of military forces, medicine and health care. Generally the smart vest contain: four Peltier coolers, which provide cooling effect; the knitted metal material, is used to increase cooling surfaces and for the smooth the temperature distribution; accumulators, that are charged by the current generated by solar cells; electronic control system, embedded in the garment, controls the optimal charging regime, the temperature of cooled garment, the level of cooling and other operating parameters. Manufacturing of smart vest with integrated microclimate control system requests for the research process to optimize the cooling function.