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Publikācija: Evaluation of Textile Pads Impregnated with Amber Suspension Effects on Skin

Publication Type Full-text conference paper published in other conference proceedings
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Evaluation of Textile Pads Impregnated with Amber Suspension Effects on Skin
Field of research 3. Medical and Health sciences
Sub-field of research 3.1 Basic medicine including pharmacy
Authors Inga Ļašenko
Elvīra Boziļeva
Nataļja Mihailova
Jūlija Novinkina
Kristīne Šalma-Ancāne
Andrejs Lūsis
Keywords hygienic textiles, amber powder
Abstract Elaboration of hygienic textiles is a complex work of textile and medicine industries. The present work studies the effect of application of textile pads impregnated with amber powder suspension on dermis, hypodermis and skin deriviates in order to determine if testing materials cause skin irritation and organism sensitization. For the evalujation of skin irritation 40 Guinea pigs were taken and divided into 5 groups. Experimental animals were treated with textile pads impregnated with amber powder suspension (5, 10, 20 %). Skin reaction has been evaluated according to the Magnuson/Clingman scale in initial and confirmatory tests 1, 24, 48 and 72h after application of the preparation and compared with experimental animal skin from the control group. For the evaluation of sensization 25 Guinea pigs were taken and divided into 5 groups. In order to induce hypersensitivity experimental animals were treated with the testing material on 1st, 6-8th, 13-15th day with application lasting for 6h. Provocation test was carried on 27-29th day to estimate if testing object’s reaction was hypersensitive. Skin reaction has been evaluated according to the Magnuson/Clingman scale. Blood of the experimental animals was tested in order to estimate the number of eosinophils (%), absolute number of eosinophil cells (l) and total IgE level (IV/ml). No skin irritation or any skin changes compared to the control group was observed during the experiments. Absolute and relative number of eosinophil cells as well as the IgE level in experimental animals’ blood wasn’t found to be increased at the end of the experiment compare to the control group.
Reference Ļašenko, I., Boziļeva, E., Mihailova, N., Novinkina, J., Šalma-Ancāne, K., Lūsis, A. Evaluation of Textile Pads Impregnated with Amber Suspension Effects on Skin. In: Ninth Int Annual ScanBalt Forum 2010, Estonia, Tallinn, 22-24 September, 2010. Tartu: Tartu University, 2010, pp.34-34.
ID 7289