The use of the mobile ad-hoc (MANET) and wireless mesh networks is spreading as well as research on the different applications of these technologies. Combination and convergence of several wireless network technologies (UMTS, WiFi, WiMax etc.) is pawing a way to ubiquitous instant connectivity allowing effective mobile peer-to-peer collaboration such as videoconferencing, “wireless office” and many other. In this paper an analysis of possible mobile pear-to-peer collaboration scenarios with different network configurations and routing protocols will be presented. Different peer-to-peer collaboration scenarios in such networks are analysed and criteria for optimisation of traffic routing are elaborated. The efficiency of DSDV and AODV routing protocols is compared for several network configurations. The results obtained are based on the network simulation with the Network Simulator (NS2) software in the grid cluster.