Energy plans of many countries anticipate an increased use of biomethane for energy supply, i.e., in power and heat production as well as in the transport sector. Existing infrastructure of natural gas storage, supply and application provides a good platform to facilitate transfer to biomethane utilization on a larger scale. One key element of the biomethane system is the upgrade of the biomass-derived synthesis gas originating from different sources, to a quality of natural gas (SNG - Synthesis Natural Gas) via the methanation process for further injection into the natural gas grid.. The maximisation of efficiency of the methanation process is of critical importance in order to make biomethane technology viable for wider application. The aim of the study was to improve efficiency of the methanation process by finding the optimum temperatures and pressure. Theoretical modelling of adiabatic and isothermal methanation processes by using thermodynamic equilibrium calculations was introduced as a method for the study. The results show the impact of temperature and pressure changes on the overall efficiency of methane production. It can be concluded from the study that knowledge about the relation between temperature, pressure and the efficiency of the methanation process makes it possible to optimize the process under various biomass synthesized gas input conditions.