Formation of Nanosized Strontium Substituted Hydroxyapatites
IOP Conference Series: Materials Science and Engineering 2012
Kārlis-Agris Gross, Anastasija Jeršova, David Grossin, Christian Rey, Artūrs Vīksna

Incorporation of specific elements into calcium phosphates offers the combination of a bioactive material and a therapeutic effect. This is important for improving the integration of implants as well as treating medical conditions. Strontium is a suitable candidate and displays the ability to stimulate bone growth and reducing bone resorption. This study investigated the formation of strontium carbonated hydroxyapatite nanoparticles from an amorphous phase. Crystallization of carbonated hydroxyapatite occurred at 585 oC, but samples with an intended 25% and 75% replacement of calcium with strontium crystallized at 624 oC. Heat treatment at the crystallization temperature revealed that strontium free apatite does not crystallize in 5 minutes, but an increasing strontium concentration leads to a higher rate of crystallization. X-ray diffraction patterns suggest that it may be difficult to include strontium, but higher strontium concentrations are possibly included with ease in the lattice. This work has produced a nanosized apatite accompanied by an amorphous phase after a short heat-treatment time. This offers a range of features that collectively show great promise for significantly enhancing the release of strontium for improved bone therapeutic effects.


DOI
10.1088/1757-899X/38/1/012032
Hipersaite
http://iopscience.iop.org/1757-899X/38/1/012032

Gross, K., Jeršova, A., Grossin, D., Rey, C., Viksna, A. Formation of Nanosized Strontium Substituted Hydroxyapatites. IOP Conference Series: Materials Science and Engineering, 2012, Vol.38, Iss.1, 012032.-012032.lpp. ISSN 1757-8981. e-ISSN 1757-899X. Pieejams: doi:10.1088/1757-899X/38/1/012032

Publikācijas valoda
English (en)
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