The Influence of Substituent on Physical-Chemical Properties of 1,4-Dihydropyridine as Delivery Agents
55th International Scientific Conference of Riga Technical University: Book of Abstracts 2014
Māra Plotniece, Marina Gosteva, Velta Ose, Kārlis Pajuste, Martins Rucins, Brigita Cekavicus, Arkadij Sobolev, Aiva Plotniece

Cationic synthetic lipid-like compounds on the 1,4-dihydropyridine scaffold possessing self-assembling properties from liposomes and can be used for gene delivery. Thecationic 1,4-DHPs are more active than DOTAP and PEI. The aim of work is to clarify the relationships of biological activity of self-assembling 1,4-DHPs and their physical-chemical properties for individual compounds.


Atslēgas vārdi
self-assembling amphiphiles, liposomes, gene delivery, antiradical activity, structure-activity relationships

Plotniece, M., Gosteva, M., Ose, V., Pajuste, K., Rucins, M., Cekavicus, B., Sobolev, A., Plotniece, A. The Influence of Substituent on Physical-Chemical Properties of 1,4-Dihydropyridine as Delivery Agents. No: 55th International Scientific Conference of Riga Technical University: Book of Abstracts, Latvija, R'iga, 14.-17. oktobris, 2014. Riga: RTU, 2014, 28.-28.lpp.

Publikācijas valoda
English (en)
RTU Zinātniskā bibliotēka.
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