Synthesis, Studies of Properties and Structure-Activity Relationships of New Delivery Systems based on the Self-Assembling Polyfunctional Pyridinium Derivatives

4th International Conference on Multifunctional, Hybrid and Nanomaterials: Abstract Book 2015
Arkadij Sobolev, Velta Ose, Kārlis Pajuste, Marina Gosteva, Māra Plotniece, Klāvs Pajuste, Martins Rucins, Brigita Cekavicus, Brigita Vīgante, Aiva Plotniece

Polyfunctional pyridinium derivatives on the 1,4-dihydropyridione scaffold possessing self-assembling properties. 1,4-DHP forms liposomes and efficiently acts as gene delivery agent. The influence of lipids head-group on transfection activity and properties of formed liposomes were studied.

Atslēgas vārdi
1,4-DHP, self-assembling, liposomes

Sobolev, A., Ose, V., Pajuste, K., Gosteva, M., Plotniece, M., Pajuste, K., Rucins, M., Cekavicus, B., Vīgante, B., Plotniece, A. Synthesis, Studies of Properties and Structure-Activity Relationships of New Delivery Systems based on the Self-Assembling Polyfunctional Pyridinium Derivatives. No: 4th International Conference on Multifunctional, Hybrid and Nanomaterials: Abstract Book, Spānija, Sitges, 9.-13. marts, 2015. Sitges: 2015, P3.033.-P3.033.lpp.

Publikācijas valoda
English (en)