Characterisation of Physical-chemical and Self-assembling Properties of Pyridinium Moieties Containing 1,4-Dihidropyridine and Pyridine Derivatives as NADH/NAD Analoques for Development of Gene Delivery Systems
Abstract Book of Riga Stradins University Scientific Conference 2016
2016
Māra Plotniece,
Klāvs Pajuste,
Oksana Petricenko,
Marina Gosteva,
Martins Rucins,
Dace Bandere,
Velta Ose,
Kārlis Pajuste,
Brigita Vīgante,
Arkadij Sobolev,
Aiva Plotniece
Two main groups of new amphiphiles: derivatives of cationic 1,4-DHP with variations of substituents at different positions of 1,4-DHP cycle and other class, oxidated form, fully aromatised compounds with head-group variations were designed and synthesised as putative delivery agents. All derivatives of cationic 1,4-DHP possess free radical quenching activity and the buffering capacity and the buffering capacity of studied N-unsubstituted 1,4-DHPs were in the pH range 6.8-8.8.
Atslēgas vārdi
Self-assembling properties, 1,4-DHP, Gene delivery
Plotniece, M., Pajuste, K., Petricenko, O., Gosteva, M., Rucins, M., Bandere, D., Ose, V., Pajuste, K., Vīgante, B., Sobolev, A., Plotniece, A. Characterisation of Physical-chemical and Self-assembling Properties of Pyridinium Moieties Containing 1,4-Dihidropyridine and Pyridine Derivatives as NADH/NAD Analoques for Development of Gene Delivery Systems. No: Abstract Book of Riga Stradins University Scientific Conference 2016, Latvija, Riga, 17.-18. marts, 2016. Riga: Riga Stradins University, 2016, 126.-126.lpp.
Publikācijas valoda
English (en)