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Publikācija: Potential of Nanofibers Webs with Sodium Chlorophyllin for the Skin Care

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Nosaukums oriģinālvalodā Potential of Nanofibers Webs with Sodium Chlorophyllin for the Skin Care
Pētniecības nozare 2. Inženierzinātnes un tehnoloģijas
Pētniecības apakšnozare 2.5. Materiālzinātne
Autori Sandra Jēgina
Silvija Kukle
Anna Šutka
Atslēgas vārdi Spruce needles, sodium chlorophyllin, electrospinning, nanofibers web, wound dressing
Anotācija The processing technologies of woods greenery are developing nowadays as a new scientific direction allowing obtain valuable natural substances for use in medicine, health care, cosmetology, agriculture and industry. Sodium chlorophyllin is one of the active substances acquired from spruce greenery. It contains derivatives of "a" and "b" chlorophyll (chlorines, sodium salts of chlorophylline acids etc.), sodium salts of resinous acids (pimaric-, isopimaric-, abietic- and labdane types), sodium salts of fatty acids (mainly oleic-, stearic- and linoleic). Due to its chemical compounds sodium chlorophyllin has bacteriostatic, regenerative and deodorant properties and could be useful as active biomedical component. Electrospun nonwoven web with integrated active chemicals released gradually is a good solution for external use as chlorophyll derivatives capitally recover tissues, heal wounds, burns and bedsores, they also decrease inflammation and neutralize toxins. For ensuring biological safety biodegrable and non-toxic polymers should be used in such composites. In the studies several compositions of sodium chlorophyllin were subjected to the investigation in a range of concentrations from 1 to 5 wt% with polyvinyl alcohol solution in water used as matrix. The diameters of electrospun nanofibers were evaluated quantitatively from atomic force microscope images. Laboratory scale microbiological tests were performed in order to evaluate the effects on the human skin dermal fibroblast cells. Results of the research showed that the sodium chlorophyllin effects such properties of the spinning solution as electrical conductivity and viscosity, diameter of nanofibers, the morphology and mechanical properties of nanomats. Microbiological test results revealed that composites with lower concentration of sodium chlorophyllin regenerate skin dermal cells, while composites with higher concentration stop the regeneration process.
DOI: 10.5593/SGEM2016/HB63/S07.017
Hipersaite: https://sgemworld.at/sgemlib/spip.php?article8780&lang=en 
Atsauce Jēgina, S., Kukle, S., Šutka, A. Potential of Nanofibers Webs with Sodium Chlorophyllin for the Skin Care. No: Nano, Bio and Green - Technologies for a Sustainable Future : International Multidisciplinary Scientific GeoConference "SGEM 2016", Austrija, Vienna, 2.-5. novembris, 2016. Sofia: STEF92 Technology Ltd., 2016, 127.-134.lpp. ISBN 978-619-7105-79-7. ISSN 1314-2704. Pieejams: doi:10.5593/SGEM2016/HB63/S07.017
Papildinformācija Citējamību skaits:
  • Scopus  0
ID 23037