The aim of this study is to develop an experimental scheme for realization of methanation reaction (CO2 + 4H2 → CH4 + 2H2O) realization. The existing experimental stands show that there are many factors and reaction parameters that may negatively act on CO2 conversion. The highest CO2 conversion rates are achieved at the temperature range of 300–400°C. Methane production efficiency also depends on reactor's space velocity, reaction's stoichiometry, catalyst's surface area and type. Nickel and Ruthenium are the most popular catalysts. Gas contaminants (like NO2, O2 and SO2) which may be in exhaust flow, act negatively on the reaction. According to this great amount of aspects acting on methanation process positive outcome special scheme was developed. It combines not only inlet gas properties, proper catalyst or reactor design selection, but also technical aspects such as preheating/mixing chamber and condensing unit design. This summarizing scheme will be used for real methnation reactor design in the future studies.