This article reviews efficiency of the fluorine, silica and zinc compounds containing textile coating conformity with the day-to-day wearing conditions of cotton knitwear used as the first level clothing to the wearer skin. Silica sol modified with the zinc acetate dehydrate was used for the weft knitted cotton single-jersey and double-jersey fabrics chemical modification. The experimental part of the presented research includes the evaluation of the fabrics structure characteristics, air and vapour permeability and water-repellent abilities. The wettability of cotton textiles were evaluated by the water contact angle before and after modification as well after hydrothermal treatment. Images of the obtained modified fibres surfaces analysed by scanning electron microscopy, and fibres surface chemical composition has been determined with dispersive X-ray analysis. Conformity of the inserted additional functions to the modified textiles were determined by testing textiles “in vivo” in experimental wearing process where 100 volunteers of different professions had participated.