Needleless electrospinning operated as a one-stage process producing nanofibres webs from spinning solutions with the corresponding to the final use properties seems has a good future prospects. Complicated spinning solution designing started with the selection of composition and components proportion, pre-processing sequence and parameters establishing for every component and for their mixing. Spinning solution viscosity and electro conductivity together with the spinning distance and intensity of electromagnetic field are main parameters determined spin ability and properties of obtained nanofibers. Influence of some pre-processing parameters of components, combinations of organic and non-organic components and their concentration influence on spinning solution viscosity and conductivity, as well on fibres diameters are under discussion.