Business Informatics is the scientific discipline targeting information processes and related phenomena in their socio-economical business context, including companies, organisations, administrations and society in general. As a field of study, it endeavours to take a systematic and analytic approach in adopting a multi-disciplinary orientation that draws theories and practices from the fields of management science, organisational science, computer science, systems engineering, information systems, information management, social science, and economics information science. The objective of this thematic issue is to bring attention to actual research on Business Informatics, as being publicized on the 19th IEEE Conference on Business Informatics (CBI 2017), July 24-27, 2017, in Thessaloniki, Greece. The conference created a productive forum for researchers and practitioners from the fields that contribute to the construction, use and maintenance of information systems and the organisational context in which they are embedded. This issue of CSIMQ comprises extended version of four CBI papers and one external article.