The incorporation of protein based polymer materials with calcium phosphate (CaP) coatings can provide excellent biological characteristics and biocompatibility with its bone-like protein-CaP composition. Calcium chloride-ethanol catalyzed hydrolysis reaction and wet precipitation method was used to prepare silk solution and to precipitate brushite, respectively, to produce brushite/silk composite powder. FTIR analysis showed that brushite absorption bands were prominent, overlapping the less intense N-H bands in silk. The most distinct absorptions from silk were N-H bands. 1 g of silk added to the 300 mL of solution media resulted in arbitrary particle attachment onto the surface of brushite crystal; most of the brushite particles were covered by the silk β-sheets phase