Primary aspect of quality of life is human protectability from various types of threats, subjection level to contemporary threats. Concept of security has become a global phenomenon. In contemporary understanding it is protectability from worldwide threats, which can lead to rapid worsening of living conditions in separate states, regions or in the world in general or even endanger existence of humanity. Economic security is one of foundation stones of national security, which can be interpreted rather widely, however it is definitely subjected to border security. Threats of economic security in states are dependent on diverse and different conditions. Frequently it is hard to tackle this issue without external assistance, because, by forming international projects for research of problems and development of solutions, experts with rich international experience, concerned institutions and organizations are involved, as well as national forces are consolidated and newest scientific conclusions are utilized. The BOMCA (Border Management Programme in Central Asia) Programme has developed to its 9th stage during the last 15 years, therefore it is objective to appraise its contribution to issues which are related to security, and promotion of trade and economic development on regional and national levels.