Urban regeneration, which includes renovation of decaying urban structures as well as renovation of dilapidated buildings, is an important economic, aesthetic and cultural factor for sustainable development planning worldwide. The revitalization of urban structures is a complex challenge, influenced by various interdisciplinary aspects, like urban socio-economic development, integrated transport and mobility solutions and others, and it requires involvement of different stakeholders at different levels in identifying and finding solutions. Technological innovations other a variety of digital tools to address modern urban governance and modelling issues, identifying problem areas with public involvement and participation that allow relevant services to respond quickly, thus improving the urban environment and the quality of life of people. However, the wide range of these tools and their mutually asynchronous use often make it difficult to choose the right tool, thus creating the risk of fragmented implementation. The aim of this paper is to propose theoretical approach for modelling of complex interactions affecting urban regeneration as well as summarize and systematize the existing digital information tools which might empower the process of regeneration.