Modern buildings impress with their dimensions and architectural solution, which is why there is a market demand for lighter construction components. As floor panels make up one of the largest parts of the total weight of a multi-storey building, reducing it is a big step to reduce the total weight of the building structures. This is usually done using hollow reinforced concrete slabs or other types of concrete solutions. This work focuses on an alternative solution. Timber-concrete composite panels reduce weight several times compared to standard concrete panels without compromising bending stiffness. Additional advantages are architectural and interior design considerations, greater spans and more free space between the timber members. In order to evaluate different solutions of timber and concrete composites, an extensive literature review was performed. The main structural details of the buildings and timber-concrete composite solutions for the current time were studied. The samples were modeled and calculated by the finite element method. Finally, timber-concrete composite panels have been tested. The object of this study is a timber-concrete composite solution, which can be either a prefabricated and prefabricated structure, or a semi-prefabricated permanent formwork that works with a concrete layer. The obvious application is in multi-storey office or residential buildings, where this solution can reduce the total materials consumption, gain more space and architectural advantages.