A roadmap for future wireless communications is expected to exploit all transmission-suitable spectrum bands, from the microwave to the optical frequencies, to support orders of magnitude faster data transfer with much lower latency than the deployed solutions nowadays. The currently under-exploited mid-infrared (mid-IR) spectrum is an essential building block for such an envisioned all-spectra wireless communication paradigm. Free-space optical (FSO) communications in the mid-IR region have recently attracted great interest due to their intrinsic merits of low propagation loss and high tolerance of atmospheric perturbations. Future development of viable mid-IR FSO transceivers requires a semiconductor source to fulfill the high bandwidth, low energy consumption, and small footprint requirements. In this context, quantum cascade laser (QCL) appears as a promising technological choice. In this work, we present an experimental demonstration of a mid-IR FSO link enabled by a 4.65-μm directly modulated QCL operating at room temperature. We achieve a transmission data rate of up to 6 Gbps over a 0.5-m link distance. This achievement is enabled by system-level characterization and optimization of transmitter and receiver power level and frequency response and assisted with advanced modulation and digital signal processing (DSP) techniques. This work pushes the QCL-based FSO technology one step closer to practical terrestrial applications, such as the fixed wireless access and the wireless mobile backhaul. Such a QCL-based solution offers a promising way towards the futuristic all-spectra wireless communication paradigm by potentially supporting the whole spectrum from the MIR to the terahertz (THz).