The chapter deals with the analysis and optimization of the operational safety and efficiency of wind energy conversion equipment. The newly proposed method of wind energy conversion involves flat blades or space prisms that perform translation motion due to the interaction with air flow. Air flow interactions with 2D moving prisms (convex, concave) are studied by computer simulation. Optimization of prism shape is made using as criteria maximum of generating force and power. Theoretical results obtained are used in the designing of new devices for energy extraction from airflow. Models of wind energy conversion devices equipped with one vibrating blade are developed (quasi translatory blade’s motion model; model with vibrating blade equipped with crank mechanism). The operation of the system due to the action of air flow is simulated with computer programs. Possibilities to obtain energy with generators of different characteristics, using mechatronic control, have been studied. The effect of wind flow with a constant speed and also with a harmonic or polyharmonic component is considered. Partial parametric optimization of the electromechanical system has been performed. The serviceability and main advantages of the proposed methods and devices are confirmed by experiments with physical models in a wind tunnel.