Electrically Charged Hydroxyapatite Enhances Immobilization and Proliferation of Osteoblasts

IFMBE Proceedings. Vol.20: 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC 2008) 2008
Jurijs Dehtjars, Nataļja Poļaka, Rachel Sammons

Hydroxyapatite (HAP) is in use to fabricate implants in dentistry and orthopaedy. To functionalise a surface of the HAP that has a direct contact to the human cells a surface electrical charge deposition is employed. The current technologies can not provide uniformity of the charge for contrarily situated surfaces. To overcome such the disadvantage a HAP hydrogenation technology has been reached. As the result the surface charge has been engineered. The charge was estimated owing to measurements of the photoelectron emission work function. The later was increased to ∼ 0.2 eV. The negatively charged HAP surface in contrast with the uncharged one attached 10 times more osteoblatic cells and increased their proliferation capacity in 1.6 time

Atslēgas vārdi
implant, hydroxyapatite, electrical charge, immobilisation, proliferation
DOI
10.1007/978-3-540-69367-3_7
Hipersaite
http://link.springer.com/chapter/10.1007/978-3-540-69367-3_7

Dehtjars, J., Poļaka, N., Sammons, R. Electrically Charged Hydroxyapatite Enhances Immobilization and Proliferation of Osteoblasts. No: IFMBE Proceedings. Vol.20: 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC 2008), Latvija, Rīga, 16.-20. jūnijs, 2008. Berlin: Springer Berlin Heidelberg, 2008, 23.-25.lpp. ISBN 9783540693666.

Publikācijas valoda
English (en)