Fucoidan/Chitosan Hydrogels for Sustained Delivery of Platelet-Rich Fibrin Containing Growth Factors

33rd Annual Conference of the European Society for Biomaterials (ESB 2023): Conference Abstracts 2023
Eva Dohle, Verena Hoffman, Ilze Salma, Sarah Al-Maawi, Shahram Ghanaati, Arita Dubņika

PRF is a second-generation platelet concentrate obtained from blood without the use of anticoagulants that includes important growth factors improving tissue regeneration. Thus, it would be beneficial to store these growth factors at the target site by the using a carrier such as a hydrogel. In this content, we combined PRF with a hydrogel carrier composed of fucoidan (FU) and chitosan (CS) due to their biocompatibility and ability to form polyelectrolyte complexes via self-assembly. Aim of this study was to determine and compare the release kinetics of different bioactive molecules from PRF and PRF/FU_CS hydrogel matrices.

Atslēgas vārdi
PRF, growth factors, hydrogels

Dohle, E., Hoffman, V., Salma, I., Al-Maawi, S., Ghanaati, S., Dubņika, A. Fucoidan/Chitosan Hydrogels for Sustained Delivery of Platelet-Rich Fibrin Containing Growth Factors. No: 33rd Annual Conference of the European Society for Biomaterials (ESB 2023): Conference Abstracts, Šveice, Davos, 4.-8. septembris, 2023. Davos: 2023, 15.-15.lpp.

Publikācijas valoda
English (en)