Multispectral Imaging Analysis of Skin Lesions in Patients with Neurofibromatosis Type 1
Journal of Clinical Medicine 2023
Emilija Vija Plorina, Kristine Saulus, Ainars Rudzitis, Norbert Kiss, Márta Medvecz, Tatjana Linova, Dmitrijs Bļizņuks, Alexey Lihachev, Ilze Lihacova

Neurofibromatosis type 1 (NF1) is a rare disease, affecting around 1 in 3500 individuals in the general population. The rarity of the disease contributes to the scarcity of the available diagnostic and therapeutic approaches. Multispectral imaging is a non-invasive imaging method that shows promise in the diagnosis of various skin diseases. The device utilized for the present study consisted of four sets of narrow-band LEDs, including 526 nm, 663 nm, and 964 nm for diffuse reflectance imaging and 405 nm LEDs, filtered through a 515 nm long-pass filter, for autofluorescence imaging. RGB images were captured using a CMOS camera inside of the device. This paper presents the results of this multispectral skin imaging approach to distinguish the lesions in patients with NF1 from other more common benign skin lesions. The results show that the method provides a potential novel approach to distinguish NF1 lesions from other benign skin lesions. © 2023 by the authors.

Atslēgas vārdi
multimodal skin imaging; multispectral imaging; neurofibromatosis type 1; non-invasive skin imaging; rare disease diagnostics

Plorina, E., Saulus, K., Rudzitis, A., Kiss, N., Medvecz, M., Linova, T., Bļizņuks, D., Lihachev, A., Lihacova, I. Multispectral Imaging Analysis of Skin Lesions in Patients with Neurofibromatosis Type 1. Journal of Clinical Medicine, 2023, Vol. 12, No. 21, Article number 6746. e-ISSN 2077-0383. Available from: doi:10.3390/jcm12216746

Publikācijas valoda
English (en)
RTU Zinātniskā bibliotēka.
E-pasts:; Tālr: +371 28399196