The article shows the actuality of piezoelectric films application for vibration diagnostic techniques that are widely used for condition monitoring of operating machines and structures in industry, transport and energy. The application of vibration diagnostics, in particular for structural monitoring, is constrained by high costs and complexity of the measurement systems, especially accelerometers. As an alternative, the use of piezoelectric film sensors is considered that cost is cheaper and size is less than strain gauge. The use of such sensors avoids calibration on the object, power supply from an additional current source, and dramatically reduce size, weight and costs of the sensor network. The properties of piezoelectric films are analyzed in comparison with strain gauges and the benefits are considered. The compatibility of piezo films with existing methods, hard and software of monitoring systems is considered. To determine the relationship between the signal generated by the piezoelectric film and parameters of vibrations, the experimental stand was developed, the studies were conducted, and the dependencies were revealed. The relationship between the signal measured by piezoelectric film and the body vibration was theoretically established and experimentally verified. The curvature of neutral line and vibration velocity (orthogonal to surface) of a vibrated body are the parameters that correspond to the piezo film’s signal.