The construction industry’s reliance on Portland cement (PC) significantly contributes to global CO₂ emissions, driving the search for sustainable binder alternatives. This study develops and evaluates novel mineral binder systems for wood wool acoustic panels with a reduced carbon footprint. Alternative binders—including calcium aluminate cement (CAC), magnesium oxychloride cement (MOC), and a gypsum-cement-pozzolan (GCP) hybrid—were combined with aluminosilicate additives such as metakaolin and liquid glass. Mechanical testing demonstrated that 20–30% metakaolin and liquid glass compo-sites achieved flexural strengths up to 2.65 MPa and densities above 490 kg/m³. The GCP system showed synergistic improvements in flexural and compressive strengths by nearly 50%, along with enhanced dimensional stability and water resistance. Life cycle assess-ment indicated substantial CO₂ emissions reductions, particularly for MOC and CAC formulations, compared to conventional Portland cement-based panels. Optimisation strategies to enhance moisture resistance and acoustic performance are discussed. These findings support the development of sustainable, low-carbon acoustic wood wool panels aligned with global decarbonisation efforts.