The research project pursued the goal of integrating creative learning methodology with e-learning in the online course of English for Specific Purposes (ESP). The sociocultural activity theory served as its conceptual basis. The research was also centered on the theoretical and empirical methodologies in defining and developing creativity in pedagogy, psychology and language teaching practice. The article describes the criteria developed for designing a creative ESP online course, which may be used in launching other creative online courses in foreign languages, and include specific course content, creative process support (creative thinking tools, techniques and software) and corresponding course administration: selection of the learning content, user support, software environment and assessment techniques. Advanced tean learning software ThinkTank and Zing were integrated in the course.