Characterisation and Dissolution of Functionalised Amorphous Calcium Phosphate Biolayers Using Single Splat Technology
Acta Biomaterialia 2011
Kārlis-Agris Gross, CJ. Young, Ezra Keebaugh, Mardi Beck, Thomas Bronts, Saeed Saber-Samandari, Daniel R. Riley

New processing routes and characterization techniques underpin further growth of biomaterials for improved performance and multifunctionality. This study investigates the characteristics and solubility of amorphous calcium phosphate (ACP) printed splats. Splats made from 20-60 μm molten hydroxyapatite particles were classified for shape (round/splashed) and cracking. Recoil of the spread droplet created a bowl-shaped splat. This has previously not been observed and could be related to the longer solidification time associated with solidification to an ACP. A central depression was created from 20 μm particles, but a bowl-shaped splat from 60 μm particles. Cracking was more prevalent for splats that solidified with an edge discontinuity. Splats immersed in pH 7.3 tris-buffer displayed dissolution followed by cracking. Cracking continued over a period of 15 minutes as dissolution induced more cracks. Further degradation occurred by delamination of splat segments. Delamination accelerated the process of splat removal. Applied to thermal spray coatings, this highlights topography and dissolution at the splat level. The use of separate splats can potentially be used as a biolayer where splats are separate, in a line or on top of each other. The combination of different composition splats can impart multifunctionality to an implant surface.


Atslēgas vārdi
Amorphous calcium phosphate; Splat; Solubility; Printing; Microfabrication; Thermal spray; Hydroxyapatite
DOI
10.1016/j.actbio.2011.01.020
Hipersaite
http://www.sciencedirect.com/science/article/pii/S1742706111000213

Gross, K., Young, C., Keebaugh, E., Beck, M., Bronts, T., Saber-Samandari, S., Riley, D. Characterisation and Dissolution of Functionalised Amorphous Calcium Phosphate Biolayers Using Single Splat Technology. Acta Biomaterialia, 2011, Vol.7, Iss.5, 2270.-2275.lpp. ISSN 1742-7061. Pieejams: doi:10.1016/j.actbio.2011.01.020

Publikācijas valoda
English (en)
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