Bioactivity of Silver Doped Hydroxyapatite Scaffolds in Simulated Body Fluids

Key Engineering Materials 2014
Lāsma Mālniece, Arita Dubņika, Dagnija Loča, Līga Bērziņa-Cimdiņa

In the present study, the in vitro bioactivity of silver-doped hydroxyapatite (HAp/Ag) scaffolds was investigated. HAp/Ag was prepared using two different modified wet precipitation methods. The X-ray powder diffraction (XRD) results showed, that sintered HAp/Ag samples prepared using method (I) contain two phases – HAp and Ag, but samples prepared by method (II) contain three different phases - HAp, Ag and AgO. After 2 month incubation period in simulated body fluid (SBF), surface of HAp/Ag scaffolds was coated with bone-like apatite. Thickness of bone-like apatite layer increased from 2 μm up to 32 μm, increasing the incubation period.

Keywords
Silver; hydroxyapatite, SBF, in vitro, bioactivity
DOI
10.4028/www.scientific.net/KEM.604.175

Poča, L., Dubņika, A., Loča, D., Bērziņa-Cimdiņa, L. Bioactivity of Silver Doped Hydroxyapatite Scaffolds in Simulated Body Fluids. Key Engineering Materials, 2014, Vol.604, pp.175-179. ISSN 1662-9795. Available from: doi:10.4028/www.scientific.net/KEM.604.175

Publication language
English (en)