Iodonium Salts are Key Intermediates in Pd-Catalyzed Acetoxylation of Pyrroles
Organic Letters
2011
Dmitrijs Lubriks,
Igors Sokolovs,
Edgars Sūna
A mild, room-temperature Pd-catalyzed acetoxylation of pyrroles with phenyliodonium acetate is described. The acetoxylation was found to proceed via the initial formation of pyrrolyl(phenyl)iodonium acetates, which were converted to acetoxypyrroles in the presence of Pd(OAc)2. The acetoxylation could also be carried out as a one-pot sequential procedure without the isolation of the intermediate iodonium salts.
Atslēgas vārdi
Pd-catalyzed acetoxylation, pyrroles
DOI
10.1021/ol201665c
Hipersaite
http://pubs.acs.org/doi/abs/10.1021/ol201665c
Lubriks, D., Sokolovs, I., Sūna, E. Iodonium Salts are Key Intermediates in Pd-Catalyzed Acetoxylation of Pyrroles. Organic Letters, 2011, Vol.13, Iss.18, 4324.-4327.lpp. ISSN 1523-7060. Pieejams: doi:10.1021/ol201665c
Publikācijas valoda
English (en)